FEIBA and PCCs
I was recently asked what I thought about FEIBA as a reversal agent for warfarin or dabigatran related bleeds. At first, I was as excited about FEIBA as the individuals who asked me my opinion of the drug for this use. A prothombin complex concentrate that had active factor VII? In effect, a four factor PCC product available in the US? A small study suggesting it effectively lowers supratherapeutic INRs?[1] Sign me up!But then I [...]